KMID : 1142020230580000011
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Blood Research 2023 Volume.58 No. 0 p.11 ~ p.12
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Practical issues in CAR T-cell therapy
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Byun Ja-Min
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Abstract
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Chimeric antigen receptor (CAR) T-cell therapy presents a revolutionary advancement in personalized cancer treatment. During the production process, the patient's own T-cells are genetically engineered to express a synthetic receptor that binds to a tumor antigen. CAR T-cells are then expanded for clinical use and infused back into the patient's body to attack cancer cells. Although CAR T-cell therapy is considered a major breakthrough in cancer immunotherapy, it is not without limitations. In this review, we discuss the barriers to effective CAR T-cell therapy in Korea.
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KEYWORD
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CAR T-cell therapy, Korea, Patient access, Barrier
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